In 2025, Cointelegraph ranks the top 10 fastest-growing blockchains by active users: 1. Solana (57M users, DeFi/NFT surge); 2. Near Protocol (51.2M, AI focus); 3. BNB Chain (46.4M, Binance-backed); 4. Base (21.5M, low-fee L2); 5. Tron (14.4M, stablecoins); 6. Bitcoin (10.8M, ETF boost); 7. Aptos (10M, Move lang); 8. Ethereum (9.6M, upgrades); 9. Polygon (7.2M, multichain); 10. Arbitrum (4M, Ethereum scaling). Growth fueled by DeFi and adoption, amid scalability hurdles.